Multiscale models for reconstitution of compacted powders

Amine Ait Ouazzou

Host Institutions

Hamburg University of Technology [ 24 months ]
Société des Produits Nestlé S.A. [ 12 months ]


Turn on Javascript!


Turn on Javascript!
Turn on Javascript!
Turn on Javascript!
Turn on Javascript!


I am an engineer in energy & propulsion systems graduated from a Franco-German double degree program between the University of Kaiserslautern and INSA Rouen Normandie. Currently pursuing a doctorate degree in engineering, working on multiscale models for reconstitution of compacted powders at the Hamburg University of Technology in partnership with Société des Produits Nestlé S.A in Lausanne.

I have been extremely fortunate to start traveling around the world and learning languages since my younger age from Moscow to Beijing and later to Rouen, Paris in France, Kaiserslautern in Germany and Montreal Canada during my studies. These experiences ignited a love for languages and exploring different culture. At the moment I speak both French and Arabic as they are my mother tongues, English fluently, German at a professional level and I am currently learning Italian!

To conclude, I would say that I love having an engineering background because it allowed me and still allows me to work on many exciting and challenging projects from completely different industries both at a national and international level. I am grateful that I had the chance to keep doing that during my studies and now in my PhD and hopefully in my future industry position.

Project Description

Compaction of powdered materials is typically performed to improve properties such as bulk density, flowability, dispersability, and stability. Using the knowledge gained through modelling and experiments these properties can be tuned by process to produce high-performance powders. A mesoscale model will be calibrated from the microscale model developed in TUSAIL and will be used for a PBM model, which takes into account all main particle properties, like size and size distribution, form, moisture, strength, rehydration and dissolution.

Specific objectives are:
  1. Develop new understanding of reconstitution of compacted powders;
  2. Develop advanced meso-particle models of reconstitution of compacted powders calibrated using microscale models developed by other ESRs;
  3. Scaling up to inform a macroscopic multi-dimensional PBM modelling considering main particle properties such as size and size distribution, form, moisture, strength and dissolution.
Expected Results:
  1. Literature study and model evaluation;
  2. Mesoscale models for different stages of reconstitution, wetting, sinking, disintegration, calibrated and validated;
  3. Detailed knowledge about the influence of compacted powder properties on their reconstitution bed at Hamburg University of Technology.
  4. Selected industrial applications established, e.g. for roller compactions

Research Output

List of related publications
  1. Amine Ait Ouazzou, Yogesh M. Harshe, Vincent Meunier, Jan Henrik Finke & Stefan Heinrich (2022), Influence of Process Parameters and Particle Size Distribution on Mechanical Properties of Tablets  Chemie Ingenieur Technik, 95: 168-177.